KiloBio

 Grubbs’ Catalyst 2nd Generation (CAS 246047-72-3) and Hoveyda-Grubbs Catalyst are two of the most widely used catalysts for olefin metathesis and ring-opening polymerization (ROMP). But which one offers the best  cost-performance ratio  for your lab? In this post, we’ll compare their prices, efficiency, and long-term savings to help you make an informed decision. Key Differences at a Glance Feature Grubbs’ Catalyst 2nd Gen Hoveyda-Grubbs Catalyst Price/Gram 165–165–220 180–180–240 Reaction Efficiency High (95% yield) High (90% yield) Substrate Tolerance Broad Broad Shelf Life 24 months 18 months Ease of Handling Air-sensitive Air-stable Cost Comparison: Grubbs’ Catalyst 2nd Generation vs. Hoveyda-Grubbs 1.  Upfront Costs Grubbs’ Catalyst 2nd Gen : 165–165–220/gram (bulk discounts available). Hoveyda-Grubbs Catalyst : 180–180–240/gram. Winner : Grubbs’ Catalyst 2nd Generation offers  lower upfront costs , especial...

 Grubbs’ Catalyst 2nd Generation (CAS 246047-72-3) is a powerful tool for organic synthesis, but its air-sensitive nature and chemical reactivity require strict safety protocols. In this guide, we’ll walk you through the  Material Safety Data Sheet (MSDS) , essential safety measures, and best practices for handling this catalyst. Whether you’re a lab manager or researcher, this guide will help you ensure compliance and protect your team. Why Safety Matters 1.  Health Risks Grubbs’ Catalyst can cause: Skin and eye irritation  upon contact. Respiratory issues  if inhaled. Toxicity  if ingested. 2.  Fire and Explosion Hazards The catalyst is  air-sensitive  and can ignite upon exposure to moisture or oxygen. Ruthenium complexes  are flammable and require inert handling. 3.  Regulatory Compliance OSHA, REACH, and GHS regulations mandate proper handling, storage, and disposal. Non...

 Grubbs’ Catalyst 2nd Generation (CAS 246047-72-3) is a powerful tool for organic synthesis, but its air-sensitive nature makes it prone to degradation. Improper storage can lead to reduced yields, failed reactions, and wasted resources. In this post, we’ll explore  proven strategies  to extend the shelf life of Grubbs’ Catalyst 2nd Generation, ensuring optimal performance and cost savings for your lab. Why Shelf Life Matters 1.  Reaction Efficiency Degraded catalyst can: Reduce yields  by 20–50%. Slow reaction kinetics , increasing synthesis time. Require higher catalyst loadings , driving up costs. 2.  Cost Savings Proper storage prevents: Waste disposal fees  from failed reactions. Repeat experiments  due to inconsistent results. Premature reordering  of catalyst. 3.  Reproducibility Stable catalyst ensures consistent results across experiments, which is critical for: A...