Grubbs’ Catalyst 2nd Generation (CAS 246047-72-3) and Hoveyda-Grubbs Catalyst are two of the most widely used catalysts for olefin metathesis and ring-opening polymerization (ROMP). But which one offers the best cost-performance ratio for your lab? In this post, we’ll compare their prices, efficiency, and long-term savings to help you make an informed decision. Key Differences at a Glance Feature Grubbs’ Catalyst 2nd Gen Hoveyda-Grubbs Catalyst Price/Gram 165–165–220 180–180–240 Reaction Efficiency High (95% yield) High (90% yield) Substrate Tolerance Broad Broad Shelf Life 24 months 18 months Ease of Handling Air-sensitive Air-stable Cost Comparison: Grubbs’ Catalyst 2nd Generation vs. Hoveyda-Grubbs 1. Upfront Costs Grubbs’ Catalyst 2nd Gen : 165–165–220/gram (bulk discounts available). Hoveyda-Grubbs Catalyst : 180–180–240/gram. Winner : Grubbs’ Catalyst 2nd Generation offers lower upfront costs , especial...
Grubbs’ Catalyst 2nd Generation (CAS 246047-72-3) is a powerful tool for organic synthesis, but its air-sensitive nature and chemical reactivity require strict safety protocols. In this guide, we’ll walk you through the Material Safety Data Sheet (MSDS) , essential safety measures, and best practices for handling this catalyst. Whether you’re a lab manager or researcher, this guide will help you ensure compliance and protect your team. Why Safety Matters 1. Health Risks Grubbs’ Catalyst can cause: Skin and eye irritation upon contact. Respiratory issues if inhaled. Toxicity if ingested. 2. Fire and Explosion Hazards The catalyst is air-sensitive and can ignite upon exposure to moisture or oxygen. Ruthenium complexes are flammable and require inert handling. 3. Regulatory Compliance OSHA, REACH, and GHS regulations mandate proper handling, storage, and disposal. Non...